The primary clinical symptoms include: hectic fever and sweating, restlessness and irritability, appetite reduction or bad appetite, and sore and pain in loin and legs.

临床表现的主要症状：潮热汗出、心烦易怒、胃纳减少或食欲差、腰膝酸痛。

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Those fighting words marked Dole as a sore loser and he lost every primary that followed.

CNN: Jeff Greenfield: McCain's harsh words